Transplanted ENSCs form functional connections with intestinal smooth muscle and restore colonic motility in nNOS-deficient mice

pubmed: wnt1 2023-12-04

Summary:

CONCLUSIONS: These results demonstrate that transplanted ENSCs can form effective neuromuscular connections and improve colonic motor function in a model of colonic dysmotility, and additionally reveal that multiple sites of cell delivery led to an improved response, paving the way for optimized clinical trial design.

Link:

https://pubmed.ncbi.nlm.nih.gov/37667277/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20231204090626&v=2.17.9.post6+86293ac

From feeds:

Exome » pubmed: wnt1

Authors:

Ryo Hotta, Ahmed Rahman, Sukhada Bhave, Rhian Stavely, Weikang Pan, Shriya Srinivasan, Geoffrey de Couto, Luis Rodriguez-Borlado, Richard Myers, Alan J Burns, Allan M Goldstein

Date tagged:

12/04/2023, 09:06

Date published:

09/04/2023, 06:00