Viral dynamics in mild and severe cases of COVID-19

Zotero / K4D COVID-19 Health Evidence Summaries Group / Top-Level Items 2020-09-22

Type Journal Article Author Yang Liu Author Li-Meng Yan Author Lagen Wan Author Tian-Xin Xiang Author Aiping Le Author Jia-Ming Liu Author Malik Peiris Author Leo L. M. Poon Author Wei Zhang URL https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(20)30232-2/abstract Series Correspondence Volume 20 Issue 6 Pages 656-657 Publication The Lancet Infectious Diseases ISSN 1473-3099, 1474-4457 Date 19/03/2020 Extra Publisher: Elsevier PMID: 32199493 Journal Abbr The Lancet Infectious Diseases DOI 10.1016/S1473-3099(20)30232-2 Library Catalog www.thelancet.com Language English Abstract Coronavirus disease 2019 (COVID-19) is a new pandemic disease. We previously reported that the viral load of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) peaks within the first week of disease onset.1,2 Findings from Feb, 2020, indicated that the clinical spectrum of this disease can be very heterogeneous.3 Here, we report the viral RNA shedding patterns observed in patients with mild and severe COVID-19.