MDIPID: Microbiota-drug interaction and disease phenotype interrelation database

Imeta. 2025 Mar 21;4(2):e70019. doi: 10.1002/imt2.70019. eCollection 2025 Apr.

ABSTRACT

The intricate bidirectional relationships among microbiota, microbial proteins, drugs, and diseases are essential for advancing precision medicine and minimizing adverse drug reactions. However, there are currently no data resources that comprehensively describe these valuable interactions. Therefore, the Microbiota-Drug Interaction and Disease Phenotype Interrelation Database (MDIPID) database was developed in this study. MDIPID is distinctive in its ability to elucidate the complex interactions among microbiota, microbial proteins, drugs/substances, and disease phenotypes, thereby providing a comprehensive interconnected network that facilitates the identification of microbial therapy targets and advances personalized medicine. This comprehensive resource is expected to become a popular repository for researchers aiming to identify microbial therapeutic targets, predict drug efficacy, and develop new therapies, thereby facilitating the advancement of personalized medicine. MDIPID can be accessed free without any login requirement at: https://idrblab.org/mdipid/.

PMID:40236778 | PMC:PMC11995188 | DOI:10.1002/imt2.70019