Ensemble learning guided survival prediction and chemotherapy benefit analysis in high-grade chondrosarcoma: A study based on the surveillance, epidemiology, and end results (SEER) database

Purpose: The chemotherapy benefit for high-grade chondrosarcoma remains controversial. Ensemble learning has better overall performance than single computational approaches for clinical decision. The primary objective was to select prognostic variables and develop optimal ensemble learning algorithms for survival prediction and analyzing chemotherapy benefit in high-grade chondrosarcoma. The secondary objective included identifying specific patient groups with estimated survival benefit for...