Association between early prophylactic heparin therapy and mortality in patients with septic shock secondary to respiratory infections: analysis based on MIMIC-IV database

CONCLUSION: Early prophylactic heparin therapy significantly reduced mortality in patients with septic shock secondary to respiratory infections, showing enhanced efficacy when administered within the first 6 hospital hours or reaching cumulative doses of ≥ 5 doses. This finding provides critical evidence for optimizing treatment strategies for septic shock.