Safety profile of linezolid in the elderly: National database analysis

BackgroundLinezolid is one of the most used antibacterials to treat resistant gram-positive infections, though its use may result in a number of toxic effects, especially in the older adults. There is lack of data derived from the real-world studies regarding safety of linezolid in the elderly.The aimTo disclose the structure of adverse drug reactions (ADRs) associated with linezolid in patients ≥60 years.Materials and methodsRetrospective analysis of spontaneous reports (SRs) from the Russian...