Bisphosphonate-related ocular adverse events: a pharmacovigilance study based on the FAERS database

This retrospective study aimed to identify and characterize signals of ocular adverse events (AEs) related to bisphosphonates (BPs) using FDA Adverse Event Reporting System (FAERS) data (2004Q1-2024Q3) to inform future safety investigations. Disproportionality analysis was conducted utilizing the reporting odds ratio (ROR), proportional reporting ratio (PRR), and Bayesian confidence propagation neural network (BCPNN) methods to identify BP-related ocular AE signals. Additionally, a modified ROR...