Trajectory of serum osmolality changes and 28-day mortality risk in patients with sepsis-associated delirium based on the MIMIC-IV database

Serum osmolality (SOSM) levels have been reported to be associated with the prognosis of critically ill patients. The purpose of this study was to analyze the impact of the trajectory of changes in SOSM on the 28-day mortality risk in patients with sepsis-associated delirium (SAD). Latent class trajectory modeling (LCTM) was employed in this retrospective cohort study of patients with SAD from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. SOSM trajectories were derived...