VDGE: a data repository of variation database for gene-edited animals across multiple species
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2024-11-12
Summary:
Gene-edited animals are crucial for addressing fundamental questions in biology and medicine and hold promise for practical applications. In light of the rapid advancement of gene editing technologies over the past decade, a dramatically increased number of gene-edited animals have been generated. Genome editing at off-target sites can, however, introduce genomic variations, potentially leading to unintended functional consequences in these animals. So, there is an urgent need to systematically...