BGCFlow: systematic pangenome workflow for the analysis of biosynthetic gene clusters across large genomic datasets
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2024-11-12
Summary:
Genome mining is revolutionizing natural products discovery efforts. The rapid increase in available genomes demands comprehensive computational platforms to effectively extract biosynthetic knowledge encoded across bacterial pangenomes. Here, we present BGCFlow, a novel systematic workflow integrating analytics for large-scale genome mining of bacterial pangenomes. BGCFlow incorporates several genome analytics and mining tools grouped into five common stages of analysis such as: (i) data...