PerturBase: a comprehensive database for single-cell perturbation data analysis and visualization
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2024-11-13
Summary:
Single-cell perturbation (scPerturbation) sequencing techniques, represented by single-cell genetic perturbation (e.g. Perturb-seq) and single-cell chemical perturbation (e.g. sci-Plex), result from the integration of single-cell toolkits with conventional bulk screening methods. These innovative sequencing techniques empower researchers to dissect perturbation effects in biological systems at an unprecedented resolution. Despite these advancements, a notable gap exists in the availability of a...