NAIRDB: a database of Fourier transform infrared (FTIR) data for nucleic acids

Nucleic Acids Res. 2024 Oct 16:gkae885. doi: 10.1093/nar/gkae885. Online ahead of print.

ABSTRACT

The Nucleic Acid InfraRed Data Bank (NAIRDB) serves as a comprehensive public repository dedicated to the archival and free distribution of Fourier transform infrared (FTIR) spectral data specific to nucleic acids. This database encompasses a collection of FTIR spectra covering diverse nucleic acid molecules, including DNA, RNA, DNA/RNA hybrids and their various derivatives. NAIRDB covers details of the experimental conditions for FTIR measurements, literature links, primary sequence data, information about experimentally determined structures for related nucleic acid molecules and/or computationally modeled 3D structures. All entries undergo expert validation and curation to maintain the completeness, consistency and quality of the data. NAIRDB can be searched by similarity of nucleic acid sequences or by direct comparison of spectra. The database is open for the submission of the FTIR data for nucleic acids. NAIRDB is available at https://nairdb.genesilico.pl.

PMID:39413200 | DOI:10.1093/nar/gkae885