VISTA Enhancer browser: an updated database of tissue-specific developmental enhancers
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2024-11-14
Summary:
Regulatory elements (enhancers) are major drivers of gene expression in mammals and harbor many genetic variants associated with human diseases. Here, we present an updated VISTA Enhancer Browser (https://enhancer.lbl.gov), a database of transgenic enhancer assays conducted in developing mouse embryos in vivo. Since the original publication in 2007, the database grew nearly 20-fold from 250 to over 4500 experiments and currently harbors over 23 500 images. The updated database provides...