dbPTM 2025 update: comprehensive integration of PTMs and proteomic data for advanced insights into cancer research
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2024-11-14
Summary:
Post-translational modifications (PTMs) are essential for modulating protein function and influencing stability, activity and signaling processes. The dbPTM 2025 update significantly expands the database to include over 2.79 million PTM sites, of which 2.243 million are experimentally validated from 48 databases and over 80 000 research articles. This version integrates proteomic data from 13 cancer types, with a particular focus on phosphoproteomic data and kinase activity profiles, allowing...