miRStart 2.0: enhancing miRNA regulatory insights through deep learning-based TSS identification
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2025-03-07
Summary:
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by binding to the 3'-untranslated regions of target mRNAs, influencing various biological processes at the post-transcriptional level. Identifying miRNA transcription start sites (TSSs) and transcription factors' (TFs) regulatory roles is crucial for elucidating miRNA function and transcriptional regulation. miRStart 2.0 integrates over 4500 high-throughput datasets across five data types, utilizing a multi-modal approach...