ClinVar: updates to support classifications of both germline and somatic variants
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2025-03-08
Summary:
ClinVar (www.ncbi.nlm.nih.gov/clinvar/) is a free, public database of human genetic variants and their relationships to disease, with >3 million variants submitted by >2800 organizations across the world. The database was recently updated to have three types of classifications: germline, oncogenicity and clinical impact for somatic variants. As for germline variants, classifications for somatic variants can be submitted in batches in a file submission or through the submission API; variants can...