AlphaLasso-a web server to identify loop and lasso motifs in 3D structure of biopolymers
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2025-06-07
Summary:
With the growing number of AI-predicted protein structures, automated methods of broad-scale analysis are required to parse this volume of data. The application of mathematically defined topologies to protein science enables such analysis. Building on the foundation of lasso peptides, complex lasso motifs are their macroscopic analogs in proteins, promising novel discoveries in drug design and the biopolymer industry. Here we present AlphaLasso, a web server designed to find and analyze...