RMPore: a comprehensive database of single-molecule RNA modifications detected by Nanopore direct RNA sequencing

Transcriptome profiling of RNA modifications is essential for uncovering and characterizing novel post-transcriptional regulatory mechanisms. However, most of the known RNA modifications remain poorly explored due to technological limitations. Nanopore direct RNA sequencing (DRS) provides an advantageous solution for transcriptome-wide RNA modification profiling, enabling simultaneous identification of any modification type in native RNA, with full-length coverage and single-molecule resolution....