scVMAP: a comprehensive platform for integrating single-cell chromatin accessibility regions with causal variants
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2025-12-10
Summary:
Integrating causal variant effects with single-cell assay for transposase-accessible chromatin with high-throughput sequencing (scATAC-seq) enables a more effective elucidation of the roles and impacts of genetic variations at the single-cell level. With the accumulation of genome-wide association studies and single-cell genomic data, there is an urgent need for comprehensive analysis and efficient exploration of these data to uncover the underlying biological processes. To address this, we...