FerrDb V3: expanding the manually curated resource for regulators and disease associations from ferroptosis to regulated cell death
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2025-12-10
Summary:
Regulated cell death (RCD) is essential to both physiological homeostasis and numerous diseases. FerrDb is a curated database for ferroptosis regulators and ferroptosis-disease associations. Though widely used, FerrDb is limited by its singular focus on ferroptosis. The field of cell death is rapidly expanding, marked by continuous discovery of novel RCD modalities. The need for a high-quality database that encompasses the entire spectrum of RCD is urgent, but none exists. Here, we introduce...