Database resources of the National Center for Biotechnology Information in 2026

Nucleic Acids Res. 2025 Dec 12:gkaf1060. doi: 10.1093/nar/gkaf1060. Online ahead of print.

ABSTRACT

The National Center for Biotechnology Information (NCBI) provides biomedical data resources including PubMed®, a repository of citations and abstracts published in life science journals, and ClinicalTrials.gov, a repository of clinical research summaries. NCBI also hosts the NIH Comparative Genomics Resource (CGR) that aims to maximize the impact of eukaryotic genome datasets. NCBI provides search and retrieval operations for most of these data from 40 distinct repositories, knowledgebases, and services. The E-utilities serve as the programming interface for most of these. Resources receiving significant updates in the past year include PubMed, PMC, Bookshelf, SciENcv, CGR, ClinicalTrials.gov, ClinVar, dbSNP, GTR, Pathogen Detection, antimicrobial resistance resources, and PubChem. These resources can be accessed through the NCBI home page at https://www.ncbi.nlm.nih.gov.

PMID:41385079 | DOI:10.1093/nar/gkaf1060