eggNOG v7: phylogeny-based orthology predictions and functional annotations

The eggNOG (evolutionary genealogy of genes: Non-supervised Orthologous Groups) database is a phylogenomic resource for orthology inference, evolutionary analysis, and functional annotation across eukaryotes, bacteria, and archaea. Previous versions relied on best reciprocal hit triangulation and clustering approaches, which, although effective, faced challenges with the computational demands of large datasets, inconsistent hierarchical orthologous group (OG) reconstruction, and inaccurate...