TEDD: a comprehensive database for translation efficiency dynamics
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2026-01-21
Summary:
Translation, a core process in central dogma, is essential for gene expression and determination of biological phenotypes. High-throughput RNA-seq, Ribo-seq, and RNC-seq have enabled large-scale measurement of translation efficiency dynamics, yet systematic quantification and integration of translation efficiency (TE), initiation efficiency (translation ratio, TR), and elongation speed (elongation velocity index, EVI) at both gene and transcript levels across diverse biological contexts remain...