MetabFlow: a comprehensive metabolic map for exogenous natural products

Exogenous natural products (NPs) undergo complex metabolic transformations both in vivo and in vitro, generating structurally diverse metabolites. Due to the involvement of host enzymes and gut microbiota, as well as the structural complexity of NPs themselves, their metabolic processes exhibit unique characteristics. However, existing metabolic transformation information remains fragmented, limiting systematic understanding of their metabolic mechanisms. To address this gap, MetabFlow...