TE-SCALE: a comprehensive database for exploring transposable element expression across human cancers at single-cell resolution

Transposable elements (TEs) are repetitive DNA sequences typically silenced in normal tissues. Their dysregulation in cancer can significantly impact oncogene activation and tumorigenesis. However, due to their repetitive nature, TEs are often excluded from gene-centric single-cell analyses. Although recent advances have enabled single-cell TE quantification, a systematic resource for exploring single-cell TE dynamics in cancer has remained lacking. To address this, we developed TE-SCALE...