SVAtlas: a comprehensive single extracellular vesicle omics resource

Extracellular vesicles (EVs) are nanoscale particles released by cells, carrying proteins, nucleic acids, lipids, and metabolites. These vesicles mediate intercellular communication and modulate disease progression across various conditions. Owing to their molecular heterogeneity and the stable bilayer protecting their cargo, EVs serve as valuable tools for early disease detection and personalized therapies. However, traditional bulk EV studies aggregate data, which can mask the distinct...