TissueNexus: a database of human tissue functional gene networks built with a large compendium of curated RNA-seq data
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2022-01-30
Summary:
Mapping gene interactions within tissues/cell types plays a crucial role in understanding the genetic basis of human physiology and disease. Tissue functional gene networks (FGNs) are essential models for mapping complex gene interactions. We present TissueNexus, a database of 49 human tissue/cell line FGNs constructed by integrating heterogeneous genomic data. We adopted an advanced machine learning approach for data integration because Bayesian classifiers, which is the main approach used for...