GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2023-02-15
Summary:
G protein-coupled receptors (GPCRs) are physiologically abundant signaling hubs routing hundreds of extracellular signal substances and drugs into intracellular pathways. The GPCR database, GPCRdb supports >5000 interdisciplinary researchers every month with reference data, analysis, visualization, experiment design and dissemination. Here, we present our fifth major GPCRdb release setting out with an overview of the many resources for receptor sequences, structures, and ligands. This includes...