Lineage Landscape: a comprehensive database that records lineage commitment across species
(database[TitleAbstract]) AND (Nucleic acids research[Journal]) 2023-06-06
Summary:
Commitment to specific cell lineages is critical for mammalian embryonic development. Lineage determination, differentiation, maintenance, and organogenesis result in diverse life forms composed of multiple cell types. To understand the formation and maintenance of living individuals, including human beings, a comprehensive database that integrates multi-omic information underlying lineage differentiation across multiple species is urgently needed. Here, we construct Lineage Landscape, a...