IPAD-DB: a manually curated database for experimentally verified inhibitors of proteins associated with Alzheimer's disease
Database (Oxford) 2025-01-23
Summary:
Alzheimer's disease (AD) is a universal neurodegenerative disease with the feature of progressive dementia. Currently, there are only seven Food and Drug Administration-approved drugs for the treatment of AD, which merely offer temporary relief from symptom deterioration without reversing the underlying disease process. The identification of inhibitors capable of interacting with proteins associated with AD plays a pivotal role in the development of effective therapeutic interventions. However,...