MANUDB: database and application to retrieve and visualize mammalian NUMTs
Database (Oxford) 2025-05-14
Summary:
There is an ongoing genetic flow from the mitochondrial genome to the nuclear genome. The mitochondrial sequences that have integrated into the nuclear genome have been shown to be drivers of evolutionary processes and cancerous transformations. In addition to their fundamental biological importance, these sequences have significant consequences for genome assembly and phylogenetic and forensic analyses as well. Previously, our research group developed a computational pipeline that provides a...