PASS2: update of database of structure-based sequence alignments

Protein sequence alignments are evolutionary models and offer as starting points for the recognition of additional members of a homologous family and design of experiments. However, the accuracy of sequence alignments is obscured at the superfamily level due to distant relationships. Where structures of proteins are available, distantly related proteins can be aligned, guided by structural features. The Protein Alignment Organized as Structural Superfamilies (PASS2) database offers such...