ABPDB: a Database of Antibacterial Peptides

IEEE Trans Comput Biol Bioinform. 2025 Jun 24;PP. doi: 10.1109/TCBBIO.2025.3582844. Online ahead of print.

ABSTRACT

Antibacterial peptides (ABPs) are a promising strategy to combat antimicrobial resistance. We constructed a comprehensive database named AntiBacterial Peptides DataBase (ABPDB) by collecting and integrating existing ABP databases. Specifically, ABPDB includes 4,872 ABPs and their sequence information, activity information, physicochemical properties and structural information. Three-dimensional structures of ABPs were predicted using AlphaFold2. In addition, we provided a service that allows users to find peptides that are structurally similar to a specific peptide. ABPDB provides user-friendly interfaces for searching, downloading and further analyzing, and is freely available at http://www.acdb.plus/ABPDB.

PMID:40811252 | DOI:10.1109/TCBBIO.2025.3582844